famFLM is a tool for the region-based association analysis using functional linear models. The famFLM algorithm also has a function for the association test between quantitative traits and multiple regional genetic variants. The famFLM tool is part of the FREGAT package.
GWAS study
Svishcheva GR, Belonogova NM, Axenovich TI "Region-Based Association Test for Familial Data under Functional Linear Models." PLoS ONE 2015; 10(6):e0128999 https://doi.org/10.1371/journal.pone.0128999
PMID: 26111046
PMCID: PMC4481467
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