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i-GSEA4GWAS is a web-based tool for the identification of pathways and genes that are associated with specific traits in genome-wide association studies (GWAS) results. It uses NP label permutation to correct gene variation to decrease biases.


GWAS study; Molecular interactions, pathways and networks; Experimental design and studies; DNA polymorphism; Genetic variation


  • Operation: Gene set testing; Pathway or network analysis; Gene-set enrichment analysis
  • Software interface: Web user interface
  • Language: -
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Not stated
  • Cost: Free
  • Version name: -
  • Credit: Project for Young Scientists Fund, Institute of Psychology, Chinese Academy of Sciences, National Natural Science Foundation of China (NSFC), the Beijing New Star Project, Beijing Municipal Science & Technology Commission Foundation.
  • Contact: g4g _at_
  • Collection: -


Zhang K, Cui S, Chang S, Zhang L, Wang J "i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study." Nucleic Acids Res. 2010; 38(Web Server issue):W90-5
PMID: 20435672
PMCID: PMC2896119

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