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Adapt-Mix

Adapt-Mix

A tool for genotype imputation in arbitrary population data. The Adapt-Mix algorithm computes estimates of local correlation structure by using a combination of information in all available reference panels and summary statistics-based methods.

Topic

Population genetics

Details

  • Operation: Imputation
  • Software interface: Command-line user interface
  • Language: Python
  • Operating system: Microsoft Windows, Mac OS X, Linux
  • License: MIT
  • Cost: Free
  • Version name: -
  • Maturity: Stable
  • Credit: U.S. National Science Foundation, The National Institutes of Health (NIH), National Institute on Minority Health And Health Disparities
  • Contact: Noah Zaitlen noah.zaitlen _at_ ucsf.edu
  • Collection: -

Publications

Park DS, Brown B, Eng C, Huntsman S, Hu D, Torgerson DG, Burchard EG, Zaitlen N "Adapt-Mix: learning local genetic correlation structure improves summary statistics-based analyses." Bioinformatics. 2015 Jun 15;31(12):i181-9. https://doi.org/10.1093/bioinformatics/btv230
PMID: 26072481
PMCID: PMC4553832

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