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GIGSEA

GIGSEA

GIGSEA (Genotype Imputed Gene Set Enrichment Analysis) is a tool to analyze imputed genotypes. The GIGSEA algorithm uses a combination of genome-wide association study (GWAS) summary statistics and eQTL to deduce differential gene expression and to examine enrichment for gene sets.

Topic

Population genetics

Details

  • Operation: Regression analysis
  • Software interface: Command-line user interface; Library
  • Language: R
  • Operating system: Microsoft Windows, Mac OS X, Linux
  • License: Not stated
  • Cost: Free
  • Version name: 0.99.25
  • Maturity: Stable
  • Credit: National Institutes of Health (NIH)
  • Contact: shijia.zhu _at_ mssm.edu | ke.hao _at_ mssm.edu
  • Collection: -

Publications

Zhu S, Qian T, Hoshida Y, Shen Y, Yu J, Hao K "GIGSEA: genotype imputed gene set enrichment analysis using GWAS summary level data." Bioinformatics. 2019 Jan 1;35(1):160-163. https://doi.org/10.1093/bioinformatics/bty529
PMID: 30010968
PMCID: PMC6298047

Download and documentation


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