GIGSEA (Genotype Imputed Gene Set Enrichment Analysis) is a tool to analyze imputed genotypes. The GIGSEA algorithm uses a combination of genome-wide association study (GWAS) summary statistics and eQTL to deduce differential gene expression and to examine enrichment for gene sets.
Population genetics
Zhu S, Qian T, Hoshida Y, Shen Y, Yu J, Hao K "GIGSEA: genotype imputed gene set enrichment analysis using GWAS summary level data." Bioinformatics. 2019 Jan 1;35(1):160-163. https://doi.org/10.1093/bioinformatics/bty529
PMID: 30010968
PMCID: PMC6298047
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