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IMPUTOR
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IMPUTOR

IMPUTOR is a tool to identify miscalled bases caused by sequencing errors and to impute genotypes. The IMPUTOR algorithm imputes erroneously called bases and missing data using a parsimony approach.



IMPUTOR

IMPUTOR is a tool to identify miscalled bases caused by sequencing errors and to impute genotypes. The IMPUTOR algorithm imputes erroneously called bases and missing data using a parsimony approach.

Topic

Population genetics

Details

  • Operation: Imputation; validation; sequence quality control; variant filtering
  • Input: FASTA, VCF
  • Output: -
  • Software interface: Command-line user interface
  • Language: Python
  • Operating system: Microsoft Windows, Mac OS X, Linux
  • License: Not stated
    • Cost: Free
  • Version name: -
    • Maturity: Stable
  • Credit: South African Medical Research Council
  • Contact: Matthew Jobin mjjobin _at_ ucsc.edu
  • Collection: -

Publications

Jobin M, Schurz H, Henn BM "IMPUTOR: Phylogenetically Aware Software for Imputation of Errors in Next-Generation Sequencing." Genome Biol Evol. 2018 Apr 1;10(5):1248-1254. https://doi.org/10.1093/gbe/evy088
PMID: 29722813
PMCID: PMC5961346


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