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MaCH is a tool for genotype imputation and haplotyping using WGS sequence data. The MaCH algorithm uses a Markov chain approach and represents sampled chromosomes as mosaics of each other.


Genotype and phenotype; Quantitative genetics


  • Operation: Imputation; Haplotype mapping
  • Software interface: Command-line user interface
  • Language: C++
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Other
  • Cost: Free
  • Version name: 1.0
  • Maturity: Stable
  • Credit: -
  • Contact: goncalo _at_ | yun_li _at_
  • Collection: -


Li Y, Willer CJ, Ding J, Scheet P, Abecasis GR "MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes." Genet Epidemiol. 2010 Dec;34(8):816-34.
PMID: 21058334
PMCID: PMC3175618

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