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Michigan Imputation Server

Michigan Imputation Server

A web-based tool for genotype imputation. The Michigan Imputation Server supports the following reference panels: 1. HapMap Release 2, 2. 1000 Genomes Phase 1, 3. 1000 Genomes Phase 3, 4. CAAPA African American, 5. Haplotype Reference Consortium, 6. Hosting your own reference panels. The Michigan Imputation Server is open source and the source code is available for download.


Population genetics


  • Operation: Imputation
  • Input: VCF, 23andMe
  • Output: -
  • Software interface: Web user interface
  • Language: Java
  • Operating system: Linux; MAC OS X; Microsoft Windows
  • License: GNU Affero General Public License v3.0
  • Cost: Free
  • Version name: 1.0.2
  • Maturity: Stable
  • Credit: Cloudgene, the U.S. National Institutes of Health,the FWF Austrian Science Fund
  • Contact:!pages/contact
  • Collection: minimac


Das S, Forer L, Schonherr S, Sidore C, Locke AE, Kwong A, Vrieze SI, Chew EY, Levy S, McGue M, Schlessinger D, Stambolian D, Loh PR, Iacono WG, Swaroop A, Scott LJ, Cucca F, Kronenberg F, Boehnke M, Abecasis GR, Fuchsberger C "Next-generation genotype imputation service and methods." Nat Genet. 2016 Oct;48(10):1284-1287.
PMID: 27571263
PMCID: PMC5157836

Fuchsberger C, Abecasis GR, Hinds DA "minimac2: faster genotype imputation." Bioinformatics. 2015 Mar 1;31(5):782-4. 2014 Oct 22.
PMID: 25338720
PMCID: PMC4341061

Download and documentation

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