PRIMAL (PedigRee IMputation ALgorithm) is a tool for genotype imputation for founder populations having pedigree data. The PRIMAL algorithm is based on an indexing procedure of Identity-By-Descent segments using clique graphs.
Livne OE, Han L, Alkorta-Aranburu G, Wentworth-Sheilds W, Abney M, Ober C, Nicolae DL "PRIMAL: Fast and accurate pedigree-based imputation from sequence data in a founder population." PLoS Comput Biol. 2015 Mar 3;11(3):e1004139. eCollection 2015 Mar. https://doi.org/10.1371/journal.pcbi.1004139
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