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Impute amino acid polymorphisms and single nucleotide polymorphisms in human luekocyte antigenes (HLA) within the major histocompatibility complex (MHC) region in chromosome 6.


Puplation genetics


  • Operation: Imputation
  • Software interface: Command-line user interface
  • Language: Java
  • Operating system: Linux
  • License: Other
  • Cost: Free
  • Version name: 1.0.3
  • Maturity: Stable
  • Credit: Howard Hughes Medical Institute, Bill and Melinda Gates Foundation, National Institutes of Health
  • Contact: Paul I.W. de Bakker pdebakker _at_ | Soumya Raychaudhuri soumya _at_ | Sherman Jia xiaomingjia _at_
  • Collection: -


Jia X, Han B, Onengut-Gumuscu S, Chen WM, Concannon PJ, Rich SS, Raychaudhuri S, de Bakker PI "Imputing amino acid polymorphisms in human leukocyte antigens." PLoS One. 2013 Jun 6;8(6):e64683.
PMID: 23762245
PMCID: PMC3675122

Pillai NE, Okada Y, Saw WY, Ong RT, Wang X, Tantoso E, Xu W, Peterson TA, Bielawny T, Ali M, Tay KY, Poh WT, Tan LW, Koo SH, Lim WY, Soong R, Wenk M, Raychaudhuri S, Little P, Plummer FA, Lee EJ, Chia KS, Luo M, De Bakker PI, Teo YY "Predicting HLA alleles from high-resolution SNP data in three Southeast Asian populations." Hum Mol Genet. 2014 Aug 15;23(16):4443-51.
PMID: 24698974

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