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Is a tool for genotype imputation. The Simpute algorithm does not require reference panels and works by evaluating two neighboring SNP loci around a missing target. It combines the estimated haplotype probabilities with LD data to predict the missing SNP genotype.


Population genetics


  • Operation: Imputation
  • Software interface: Command-line user interface
  • Language: -
  • Operating system: Microsoft Windows
  • License: Not stated
  • Cost: Free
  • Version name: -
  • Maturity: Stable
  • Credit: -
  • Contact: Chuan Yi Tang cytang _at_ | Wen-Ping Hsieh wphsieh _at_
  • Collection: -


Lin YJ, Chang CT, Tang CY, Hsieh WP "Simpute: an efficient solution for dense genotypic data." Biomed Res Int. 2013;2013:813912.
PMID: 23509783
PMCID: PMC3581137

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