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TIGAR (Transcriptome-Intergrated Genetic Association Resource) is a tool for genotype imputation of transcriptome data. The TIGAR algorithm uses a nonparametric Bayesian method.


Population genetics


  • Operation: Imputation
  • Software interface: Command-line user interface
  • Language: Python,BASH
  • Operating system: Microsoft Windows, Mac OS X, Linux
  • License: Not stated
  • Cost: Free
  • Version name: -
  • Credit: Department of Hu-man Genetics at Emory University School of Medicine, National Institutes of Health (NIH), he Dermatology Foundation, theArthritis National Research Foundation, the National PsoriasisFoundation, he Illinois Department of Public Health, theTranslational Genomics Research Institute.
  • Contact: jingjing.yang _at_
  • Collection: -


Nagpal S, Meng X, Epstein MP, Tsoi LC, Patrick M, Gibson G, De Jager PL, Bennett DA, Wingo AP, Wingo TS, Yang J "TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits." Am J Hum Genet. 2019 Aug 1;105(2):258-266. 2019 Jun 20.
PMID: 31230719
PMCID: PMC6698804

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