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TIGAR

TIGAR

TIGAR (Transcriptome-Intergrated Genetic Association Resource) is a tool for genotype imputation of transcriptome data. The TIGAR algorithm uses a nonparametric Bayesian method.

Topic

Population genetics

Details

  • Operation: Imputation
  • Software interface: Command-line user interface
  • Language: Python,BASH
  • Operating system: Microsoft Windows, Mac OS X, Linux
  • License: Not stated
  • Cost: Free
  • Version name: -
  • Credit: Department of Hu-man Genetics at Emory University School of Medicine, National Institutes of Health (NIH), he Dermatology Foundation, theArthritis National Research Foundation, the National PsoriasisFoundation, he Illinois Department of Public Health, theTranslational Genomics Research Institute.
  • Contact: jingjing.yang _at_ emory.edu
  • Collection: -

Publications

Nagpal S, Meng X, Epstein MP, Tsoi LC, Patrick M, Gibson G, De Jager PL, Bennett DA, Wingo AP, Wingo TS, Yang J "TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits." Am J Hum Genet. 2019 Aug 1;105(2):258-266. 2019 Jun 20. https://doi.org/10.1016/j.ajhg.2019.05.018
PMID: 31230719
PMCID: PMC6698804

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