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simuRare

simuRare

A tool for genotype imputation. The simuRare algorithm uses an aggregate of a logistic regression-based imputation and resampling to simulate rare and common single nucleotide polymorphism (SNP).

Topic

Population genetics; Simulation experiment

Details

  • Operation: Simulated gene expression data generation; Imputation
  • Software interface: Command-line user interface
  • Language: R
  • Operating system: Linux; Microsoft Windows
  • License: Not stated
  • Cost: Free
  • Version name: 1.0 for R v 2.15 and 1.1 for R v 3.0
  • Maturity: Stable
  • Credit: The National Institute on Drug Abuse,the National Institutes of Health.
  • Contact: Heping Zhang heping.zhang _at_ yale.edu
  • Collection: -

Publications

Xu Y, Wu Y, Song C, Zhang H "Simulating realistic genomic data with rare variants." Genet Epidemiol. 2013 Feb;37(2):163-72. 17. https://doi.org/10.1002/gepi.21696
PMID: 23161487
PMCID: PMC3543480


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