For better experience, turn on JavaScript!



The tool analyses multiple protein sequence alignments to find correlated residues. The algorithm assumes that functionally related residues are due to dependent evolution. The calculations are based on physicochemical properties.


Small molecules; Protein folding, stability and design; Proteins; Protein folds and structural domains; Protein sites, features and motifs


  • Operation: Sequence alignment analysis (site correlation); Sequence alignment analysis (conservation); Multiple sequence alignment; Protein sequence analysis
  • Input: FASTA; Clustal; NBRF Nexus; GCG
  • Output: ASCII; HTML; GIF
  • Software interface: Web user interface
  • Language: -
  • Operating system: Linux; Mac OS X
  • License: Not stated
  • Cost: Free
  • Version name: -
  • Credit: -
  • Contact: ada _at_
  • Collection: -


Download and documentation

If you find errors, please report here.