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MARS is a multiple sequence alignment (MSA) tool specifically designed for the alignment of sequences from circular genomes, such as mitochondria and viral genome sequences.


Sequence analysis; Phylogeny


  • Operation: Multiple sequence alignment
  • Input: FASTA
  • Output: FASTA
  • Software interface: Command-line user interface
  • Language: C++
  • Operating system: Linux; Mac OS X
  • License: GNU General Public License v3
  • Cost: Free
  • Version name: -
  • Credit: EPSRC grant (Doctoral Training Grant #EP/M50788X/1).
  • Contact: solon.pissis _at_
  • Collection: -


Lorraine A. K. Ayad, Solon P. Pissis "MARS: improving multiple circular sequence alignment using refined sequences" BMC Genomics201718:86
PMID: 28088189
PMCID: PMC5237495

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