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MSARC a multiple sequence alignment (MSA) tool that constructs alignments without guide trees. The Authors claim their method to outperform BAliBASE on "sequence sets whose evolutionary distances are difficult to represent by a phylogenetic tree."


Phylogeny; Sequence analysis; Nucleic acid sites, features and motifs; Nucleic acid structure analysis; Sequence sites, features and motifs OPERATION=Multiple sequence alignment


  • Operation: Multiple sequence alignment
  • Input: FASTA
  • Output: MSF
  • Software interface: Command-line user interface
  • Language: Python
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Not stated
  • Cost: Free
  • Version name: 1.2
  • Maturity: MATURITY=Stable
  • Credit: Polish Ministry of Science and Higher Education [N N519 652740].
  • Contact: dojer _at_
  • Collection: -


Modzelewski M, Dojer N "MSARC: Multiple sequence alignment by residue clustering." Algorithms Mol Biol. 2014 Apr 16;9:12.
PMID: 24735785

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