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OD-seq is a software program for detecting outliers in multiple sequence alignments (MSA). It works by finding sequences with an inconsistent average distance to sequences present in the multiple alignment.


Sequence analysis


  • Operation: Sequence comparison; Multiple sequence alignment; validation
  • Input: FASTA
  • Output: -
  • Software interface: Command-line user interface
  • Language: C++
  • Operating system: Linux
  • License: Not stated
  • Cost: Free
  • Version name: -
  • Credit: -
  • Contact: peter.jehl _at_
  • Collection: -


Jehl P, Sievers F, Higgins DG "OD-seq: outlier detection in multiple sequence alignments" BMC Bioinformatics. 2015 Aug 25;16:269
PMID: 26303676
PMCID: PMC4548304

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