Phylo

Phylo is a web-based tool to optimize multiple sequence alignment (MSA) of DNA using humans' ability to recognize patterns. Phylo represents a multiple sequence alignment as a puzzle, a game where users manipulate colored shapes. The approach does not require extensive prior knowledge of biology.

Details
Topic
Publications
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Phylo

Topic

Sequence analysis; Nucleic acids

Details

Operation: Multiple sequence alignment; Sequence alignment; Multiple sequence alignment
Software interface: Web user interface; mobile app
Language: -
Operating system: Linux; Mac OS X; Microsoft Windows
License: Not stated

Cost

Version name: -

Maturity:

Credit: Natural Sciences and Engineering Research Council of Canada;McGill University;Nokia.
Contact: blanchem _at_ mcb.mcgill.ca | jeromew _at_ cs.mcgill.ca
Collection: -

Publications

Kawrykow A, Roumanis G, Kam A, Kwak D, Leung C, Wu C, Zarour E; Phylo players, Sarmenta L, Blanchette M, Waldispühl J "Phylo: a citizen science approach for improving multiple sequence alignment." PLoS One. 2012;7(3):e31362. https://doi.org/10.1371/journal.pone.0031362
PMID: 22412834
PMCID: PMC3296692

See more details

Kwak D, Kam A, Becerra D, Zhou Q, Hops A, Zarour E, Kam A, Sarmenta L, Blanchette M, Waldispühl J "Open-Phylo: a customizable crowd-computing platform for multiple sequence alignment." Genome Biol. 2013;14(10):R116. https://doi.org/10.1186/gb-2013-14-10-r116
PMID: 24148814
PMCID: PMC4014878