A multiple protein sequence alignment tool that is based on probabilistic models, employing a column-oriented and selective consistency in aligment refinement instead of commonly used strategies of increased alignment quality. The Authors claim Quick-Probs 2 to be "noticeably" better than ClustalΩ and MAFFT.
Sequence analysis; Proteins; Gene and protein families
Gudyś A, Deorowicz S "QuickProbs 2: Towards rapid construction of high-quality alignments of large protein families." Sci Rep. 2017 Jan 31;7:41553. https://doi.org/10.1038/srep41553
Gudyś A, Deorowicz S "QuickProbs--a fast multiple sequence alignment algorithm designed for graphics processors." PLoS One. 2014 Feb 25;9(2):e88901. https://doi.org/10.1371/journal.pone.0088901
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