A web server for T-Coffee tools for evaluating and A web server at The Centre for Genomic Regulation (CRG) provides T-Coffee tools for assessing and handling multiple sequence alignments (MSAs) of nucleotide and amino acid sequences and related structures. The web server provides the following methods: M-Coffee, R-Coffee, Expresso, PSI-Coffee, and iRMSD-APDB.manipulating multiple alignments of DNA, RNA, protein sequences and structures. Includes M-Coffee, R-Coffee, Expresso, PSI-Coffee, iRMSD-APDB.
Sequence analysis; Proteomics; Genomics
Di Tommaso P, Moretti S, Xenarios I, Orobitg M, Montanyola A, Chang JM, Taly JF, Notredame C "T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension" Nucleic Acids Res. 2011 Jul;39(Web Server issue):W13-7. https://doi.org/10.1093/nar/gkr245
Notredame C, Higgins DG, Heringa J "T-Coffee: A novel method for fast and accurate multiple sequence alignment." J Mol Biol. 2000 Sep 8;302(1):205-17. https://doi.org/10.1006/jmbi.2000.4042
Magis C, Taly JF, Bussotti G, Chang JM, Di Tommaso P, Erb I, Espinosa-Carrasco J, Notredame C "T-Coffee: Tree-based consistency objective function for alignment evaluation." Methods Mol Biol. 2014;1079:117-29. https://doi.org/10.1007/978-1-62703-646-7_7
Taly JF, Magis C, Bussotti G, Chang JM, Di Tommaso P, Erb I, Espinosa-Carrasco J, Kemena C, Notredame C "Using the T-Coffee package to build multiple sequence alignments of protein, RNA, DNA sequences and 3D structures." Nat Protoc. 2011 Nov;6(11):1669-82. https://doi.org/10.1038/nprot.2011.393
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