A web-based tool for PSI/TM-Coffee at The Centre for Genomic Regulation (CRG). The tool is specifically constructed to construct multiple sequence alignments (MSAs) of transmembrane proteins. It can use transmembrane databases for fast extension of homology.
Sequence analysis; Proteomics; Genomics
Floden EW, Tommaso PD, Chatzou M, Magis C, Notredame C, Chang JM "PSI/TM-Coffee: a web server for fast and accurate multiple sequence alignments of regular and transmembrane proteins using homology extension on reduced databases." Nucleic Acids Res. 2016 Jul 8;44(W1):W339-43. https://doi.org/10.1093/nar/gkw300
PMID: 27106060
PMCID: PMC4987888
Chang JM, Di Tommaso P, Taly JF, Notredame C "Accurate multiple sequence alignment of transmembrane proteins with PSI-Coffee." BMC Bioinformatics. 2012 Mar 28;13 Suppl 4:S1. https://doi.org/10.1186/1471-2105-13-S4-S1
PMID: 22536955
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