4SALE is a tool for the asynchronous alignment of RNA secondary structures. 4SALE has a graphical interface written in Java, provides synchronous editing of the sequence alignments and secondary structures, and direct access to the ITS2 Database. The features include the ability to select multiple sections of an alignment, highlighting of sequence-motifs by pattern matching, visualization of sequence information using sequence logos or bars, and reordering of sequences.
Sequence analysis; Structure analysis; RNA
Seibel PN, Müller T, Dandekar T, Wolf M "Synchronous visual analysis and editing of RNA sequence and secondary structure alignments using 4SALE." BMC Res Notes 2008 https://doi.org/10.1186/1756-0500-1-91
PMID: 18854023
PMCID: PMC2587473
Wolf M, Koetschan C, Müller T "ITS2, 18S, 16S or any other RNA - simply aligning sequences and their individual secondary structures simultaneously by an automatic approach." Gene, 2014 https://doi.org/10.1016/j.gene.2014.05.065
PMID: 24881812
Seibel PN, Müller T, Dandekar T, Schultz J, Wolf M "4SALE--a tool for synchronous RNA sequence and secondary structure alignment and editing." BMC Bioinformatics, 2006 https://doi.org/10.1186/1471-2105-7-498
PMID: 17101042
PMCID: PMC1637121
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