BEAM (BEAr Motifs finder) is a web-based tool to identify and analyze RNA secondary structures. The BEAM algorithm computes the statistical significance of each motif, uses information from the RFAM database of families of homologous RNAs, produces logos and shared positions for each of the motifs. It uses RNAfold (MFE) or RNAstructure (MEA) for folding. The BEAM algorithm transforms RNA secondary structures into character strings to speed up to achieve rapid computation..
RNA; Nucleic acid sites, features and motifs; Nucleic acid structure analysis
Pietrosanto M, Adinolfi M, Casula R, Ausiello G, Ferrè F, Helmer-Citterich M "BEAM web server: a tool for structural RNA motif discovery." Bioinformatics 2018; 34(6):1058-1060 https://doi.org/10.1093/bioinformatics/btx704
PMID: 29095974
PMCID: PMC5860439
Pietrosanto M, Mattei E, Helmer-Citterich M, Ferrè F "A novel method for the identification of conserved structural patterns in RNA: From small scale to high-throughput applications." Nucleic Acids Res, 2016 https://doi.org/10.1093/nar/gkw750
PMID: 27580722
PMCID: PMC5062999
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