CARNAC is a tool for the analysis and prediction of conserved secondary structures in homologous RNAs. The CARNAC algorithm uses a thermodynamic model to minimize the energies and mutual information in sequences. This way, CARNAC can predict sequences that share a secondary structure without the need for them to be aligned.
RNA; Structure prediction; Nucleic acid structure analysis; Functional, regulatory and non-coding RNA; Virology
Touzet H, Perriquet O "CARNAC: folding families of related RNAs." Nucleic Acids Res. 2004; 32(Web Server issue):W142-5 https://doi.org/10.1093/nar/gkh415
PMID: 15215367
PMCID: PMC441553
Perriquet O, Touzet H, Dauchet M "Finding the common structure shared by two homologous RNAs." Bioinformatics, 2003 https://doi.org/10.1093/bioinformatics/19.1.108
PMID: 12499300
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