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CURVES+

CURVES+

Curves+ is a web-based tool to analyze and visualize nucleic acid structures, the helical backbone and groove parameters.

Topic

Nucleic acid structure analysis; Nucleic acids; Structure prediction; Sequence composition, complexity and repeats; Nucleic acid sites, features and motifs

Details

  • Operation: Nucleic acid structure comparison; Nucleic acid melting curve plotting; Nucleic acid structure prediction; Nucleic acid structure analysis
  • Software interface: Web user interface
  • Language: Fortran
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Not stated
  • Cost: Free
  • Version name: -
  • Maturity: Mature
  • Credit: CNRS, ANR Blanc project ALADDIN, IBISA project GRISBI.
  • Contact: r.lavery _at_ ibcp.fr
  • Collection: -

Publications

Blanchet C, Pasi M, Zakrzewska K, Lavery R "CURVES+ web server for analyzing and visualizing the helical, backbone and groove parameters of nucleic acid structures." Nucleic Acids Res. 2011; 39(Web Server issue):W68-73 https://doi.org/10.1093/nar/gkr316
PMID: 21558323
PMCID: PMC3125750


Lavery R, Zakrzewska K, Beveridge D, Bishop TC, Case DA, Cheatham T 3rd, Dixit S, Jayaram B, Lankas F, Laughton C, Maddocks JH, Michon A, Osman R, Orozco M, Perez A, Singh T, Spackova N, Sponer J "A systematic molecular dynamics study of nearest-neighbor effects on base pair and base pair step conformations and fluctuations in B-DNA." Nucleic Acids Res, 2010 https://doi.org/10.1093/nar/gkp834
PMID: 19850719
PMCID: PMC2800215


Lavery R, Maddocks JH, Pasi M, Zakrzewska K "Analyzing ion distributions around DNA." Nucleic Acids Res, 2014 https://doi.org/10.1093/nar/gku504
PMID: 24906882
PMCID: PMC4081102


Dans PD, Faustino I, Battistini F, Zakrzewska K, Lavery R, Orozco M "Unraveling the sequence-dependent polymorphic behavior of d(CpG) steps in B-DNA." Nucleic Acids Res, 2014 https://doi.org/10.1093/nar/gku809
PMID: 25223784
PMCID: PMC4191396


Pasi M, Maddocks JH, Beveridge D, Bishop TC, Case DA, Cheatham T 3rd, Dans PD, Jayaram B, Lankas F, Laughton C, Mitchell J, Osman R, Orozco M, Pérez A, Petkevičiūtė D, Spackova N, Sponer J, Zakrzewska K, Lavery R "μABC: a systematic microsecond molecular dynamics study of tetranucleotide sequence effects in B-DNA." Nucleic Acids Res, 2014 https://doi.org/10.1093/nar/gku855
PMID: 25260586
PMCID: PMC4231739


Pasi M, Maddocks JH, Lavery R "Analyzing ion distributions around DNA: sequence-dependence of potassium ion distributions from microsecond molecular dynamics." Nucleic Acids Res, 2015 https://doi.org/10.1093/nar/gkv080
PMID: 25662221
PMCID: PMC4344516


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