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OligoCalc

OligoCalc

OligoCalc is a tool to calculate the melting temperature, concentration, molecular weight, absorbance at 260 nanometers, and physical properties of single- and double-stranded DNA and RNA molecules. OligoCalc algorithm recognizes 5’ and 3’ chemical modifications and predicts potential hairpin loops.

Topic

Nucleic acid structure analysis; Physics; Protein modifications; DNA; RNA

Details

  • Operation: Protein molecular weight calculation; Protein property calculation; Nucleic acid thermodynamic property calculation
  • Software interface: Web user interface
  • Language: Javascript
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Not stated
  • Cost: Free
  • Version name: 3.27
  • Maturity: Mature
  • Credit: Northwestern University, The Feinberg School of Medicine and the Robert H. Lurie Comprehensive Cancer Center of Northwestern University
  • Contact: wakibbe _at_ northwestern.edu
  • Collection: -

Publications

Kibbe WA "OligoCalc: an online oligonucleotide properties calculator." Nucleic Acids Res. 2007; 35(Web Server issue):W43-6 https://doi.org/10.1093/nar/gkm234
PMID: 17452344
PMCID: PMC1933198


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