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VarGibbs

VarGibbs

VarGibbs Tool computes nearest-neighbor DNA entropies and initiation parameters from experimental melting temperatures. The VarGibbs algorithm is similar to the Peyrard-Bishop nearest-neighbor model.

Topic

DNA; Structure analysis; Computational chemistry; Nucleic acid structure analysis

Details

  • Operation: Nucleic acid thermodynamic property calculation
  • Software interface: Command-line user interface
  • Language: C++
  • Operating system: Linux
  • License: CC BY-NC 3.0
  • Cost: Free
  • Version name: 2.2
  • Credit: Fundação de Amparo à Pesquisa do Estado de Minas Gerais (Fapemig), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
  • Contact: gweberbh _at_ gmail.com
  • Collection: -

Publications

Weber G "Optimization method for obtaining nearest-neighbour DNA entropies and enthalpies directly from melting temperatures." Bioinformatics 2015; 31(6):871-7 https://doi.org/10.1093/bioinformatics/btu751
PMID: 25391397


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