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3V

3V

3V (Voss Volume Voxelator) is a tool to compute internal volumes from RNA and protein structures, such as deep clefts, channels, and cavities. The 3V algorithm computes the internal volumes using the differences between two rolling-probe solvent-excluded surfaces, probe radiuses, and solvent radiuses.

Topic

Imaging; Protein structural motifs and surfaces; RNA; Probes and primers; Nucleic acid structure analysis

Details

  • Operation: Image analysis; Molecular surface calculation; Protein property calculation; Protein model validation; Protein structure analysis
  • Input: RNA and protein structures
  • Output: volumetric representations in images, 3V files
  • Software interface: Command-line user interface; Web user interface
  • Language: C++
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GNU General Public License v3
  • Cost: Free
  • Version name: 1.2
  • Credit: National Institutes of Health, the AL Williams Professorship funds
  • Contact: vossman77 _at_ yahoo.com
  • Collection: -

Publications

Voss NR, Gerstein M "3V: cavity, channel and cleft volume calculator and extractor." Nucleic Acids Res. 2010; 38(Web Server issue):W555-62 https://doi.org/10.1093/nar/gkq395
PMID: 20478824
PMCID: PMC2896178


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