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ExMS

ExMS

ExMS is a tool for the analysis of hydrogen exchange-mass spectrometry (HX-MS) data. The ExMS algorithm finds individual isotopic peaks and isotopic envelopes of a list of peptides identified by MS/MS, makes various tests and can process data from many sequential HX time points with no operator intervention.

Topic

Proteomics; Proteomics experiment

Details

  • Operation: Peak detection; Validation of peptide-spectrum matches; Protein hydrogen exchange rate calculation; Deisotoping; Plotting
  • Software interface: Graphical user interface
  • Language: MATLAB
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Other
  • Cost: Free
  • Version name: -
  • Maturity: Stable
  • Credit: National Institutes of Health (NIH), National Science Foundation (NSF), the Mathers Foundation.
  • Contact: kanz _at_ mail.med.upenn.edu
  • Collection: -

Publications

Kan ZY, Mayne L, Chetty PS, Englander SW "ExMS: data analysis for HX-MS experiments." J. Am. Soc. Mass Spectrom. 2011; 22(11):1906-15 https://doi.org/10.1007/s13361-011-0236-3
PMID: 21952778
PMCID: PMC3398505


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