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MASCOT
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MASCOT

Mascot is a web-based tool to identify proteins by integrating 1. peptide molecular weights from the digestion of a protein by an enzyme, 2. tandem mass spectrometry (MS/MS) data, 3. combine mass data with amino acid sequence data. Mascot supports AB Sciex, Agilent, Bruker, Jeol, Shimadzu, Thermo Scientific, and Waters instruments.



MASCOT

Mascot is a web-based tool to identify proteins by integrating 1. peptide molecular weights from the digestion of a protein by an enzyme, 2. tandem mass spectrometry (MS/MS) data, 3. combine mass data with amino acid sequence data. Mascot supports AB Sciex, Agilent, Bruker, Jeol, Shimadzu, Thermo Scientific, and Waters instruments.

Topic

Proteomics; Proteomics experiment

Details

  • Operation: Protein fragment weight comparison; Protein identification; Blind peptide database search; Peptide database search; Tag-based peptide identification; Peptide identification; Target-Decoy
  • Software interface: Web user interface
  • Language: -
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Proprietary
    • Cost: Partly free
  • Version name: -
  • Credit: The Imperial CancerResearch Fund.
  • Contact: info _at_ matrixscience.com | http://www.matrixscience.com/contact.html
  • Collection: -

Publications

Perkins DN, Pappin DJ, Creasy DM, Cottrell JS "Probability-based protein identification by searching sequence databases using mass spectrometry data." Electrophoresis 1999; 20(18):3551-67 https://doi.org/10.1002/(SICI)1522-2683(19991201)20:18<3551::AID-ELPS3551>3.0.CO;2-2
PMID: 10612281


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