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MSstats

MSstats

MSstats is an R tool to analyze quantitative mass spectrometry data and proteomics. The MSstats algorithm includes functions for the differential detection of proteins in mass spectrometry (MS) with chromatography-based quantification, characterization of MS assays, quality control, and system suitability testing.

Topic

Proteomics; Proteomics experiment; Statistics and probability; Workflows

Details

  • Operation: Statistical modelling; Data handling; Differential protein expression analysis; Statistical inference; Quantification; Standardisation and normalisation; Formatting; Plotting; Heat map generation
  • Software interface: Command-line user interface
  • Language: R
  • Operating system: Linux; Mac OS X
  • License: Artistic-2.0
  • Cost: Free
  • Version name: 3.11.3
  • Credit: National Science Foundation (NSF)
  • Contact: Olga Vitek o.vitek _at_ neu.edu | Sicheng Hao hao.sic _at_ husky.neu.edu | Meena Choi nchoi67 _at_ gmail.com |Ting Huang thuang0703 _at_ gmail.com
  • Collection: -

Publications

Choi M, Chang CY, Clough T, Broudy D, Killeen T, MacLean B, Vitek O "MSstats: an R package for statistical analysis of quantitative mass spectrometry-based proteomic experiments." Bioinformatics 2014; 30(17):2524-6 https://doi.org/10.1093/bioinformatics/btu305
PMID: 24794931


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