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REPRO

REPRO

REPRO is a tool for identification distantly located repeated sequences in proteins. The REPRO algorithm first finds n (n specified by user) top-scoring non-overlapping local alignments by a modified Smith-Waterman method and clusters them using a graph-based process.

Topic

Sequence composition, complexity and repeats; Nucleic acid structure analysis

Details

  • Operation: Repeat sequence detection; Local alignment
  • Software interface: Web user interface
  • Language: C
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Not stated
  • Cost: Free
  • Version name: -
  • Credit: The Medical Research Council
  • Contact: rgeorge _at_ nimr.mrc.ac.uk | heringa _at_ cs.vu.nl
  • Collection: -

Publications

George RA, Heringa J "The REPRO server: finding protein internal sequence repeats through the Web." Trends Biochem. Sci. 2000; 25(10):515-7 https://doi.org/10.1016/s0968-0004(00)01643-1
PMID: 11203383


Heringa J, Argos P "A method to recognize distant repeats in protein sequences." Proteins, 1993 https://doi.org/ 10.1002/prot.340170407
PMID: 8108381


Heringa J "Two strategies for sequence comparison: profile-preprocessed and secondary structure-induced multiple alignment." Comput Chem, 1999 https://doi.org/10.1016/s0097-8485(99)00012-1
PMID: 10404624


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