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StavroX
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StavroX

StavroX and MeroX are a single tool for the analysis of complex peptide-peptide cross-links. The Authors have evaluated the StavroX algorithm with 1. the complex between calmodulin and a peptide derived from Munc13, 2. an N-terminal beta-laminin fragment, and (3) the complex between guanylyl cyclase-activating protein-2 and a peptide derived from retinal guanylyl cyclase.



StavroX

StavroX and MeroX are a single tool for the analysis of complex peptide-peptide cross-links. The Authors have evaluated the StavroX algorithm with 1. the complex between calmodulin and a peptide derived from Munc13, 2. an N-terminal beta-laminin fragment, and (3) the complex between guanylyl cyclase-activating protein-2 and a peptide derived from retinal guanylyl cyclase.

Topic

Proteomics; Proteomics experiment

Details

  • Operation: Protein feature detection; Protein structure analysis
  • Input: FASTA, .mgf, .pkl, .mzXML, .mzML
  • Output: -
  • Software interface: Graphical user interface
  • Language: Java
  • Operating system: Microsoft Windows
  • License: Other
    • Cost: Free
  • Version name: 2.0.x
  • Credit: DFG (German Research Foundation, theGraduiertenkolleg 1591 “Posttranscriptional Control of GeneExpression: Mechanisms and Role in Pathogenesis”, the Graduiertenkolleg 1026 “Conformational Transitions in Macromolecular Interactions” at the Martin-Luther University Halle-Wittenberg, the EU(LUNGTARGET project).
  • Contact: michael.goetze _at_ biochemtech.uni-halle.de | webmaster _at_ ms-utils.org
  • Collection: ms-utils

Publications

Götze M, Pettelkau J, Schaks S, Bosse K, Ihling CH, Krauth F, Fritzsche R, Kühn U, Sinz A "StavroX--a software for analyzing crosslinked products in protein interaction studies." J. Am. Soc. Mass Spectrom. 2012; 23(1):76-87 https://doi.org/10.1007/s13361-011-0261-2
PMID: 22038510


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