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muxQuant

muxQuant

muxQuant is a tool to multiplex relative quantitation of peptides and proteins from mass LC-MS data in mzXML. The muxQuant algorithm uses the same code as the FFTW library, which is used by AUTOHD, the Random Access Minimal Parser (RAMP) library to read data in mzXML, selects isotopic envelopes for peptides, fits computed envelopes using the weighted isotopic distributions for each level of stable isotopes and peptides.

Topic

Proteomics; Proteomics experiment

Details

  • Operation: Isotopic distributions calculation; Metabolic labeling; Protein quantification; Labeled quantification; Isotope-coded protein label
  • Software interface: Command-line user interface
  • Language: C
  • Operating system: Linux
  • License: CC-BY-SA-3.0
  • Cost: Free
  • Version name: -
  • Credit: -
  • Contact: magnus.palmblad _at_ gmail.com
  • Collection: -

Publications

Palmblad M, Mills DJ, Bindschedler LV "Heat-shock response in Arabidopsis thaliana explored by multiplexed quantitative proteomics using differential metabolic labeling." J. Proteome Res. 2008; 7(2):780-5 https://doi.org/10.1021/pr0705340
PMID: 18189342


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