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Boiler
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Boiler

A tool to compress RNA-seq alignments. The Boiler algorithm extracts summary, coverage, and distribution data from the sequence alignments. By discarding individual sequence data, the resulting data set is small.



Boiler

A tool to compress RNA-seq alignments. The Boiler algorithm extracts summary, coverage, and distribution data from the sequence alignments. By discarding individual sequence data, the resulting data set is small.

Topic

RNA-seq; Data management

Details

  • Operation: Sequence alignment; Formatting
  • Input: SAM
  • Output: -
  • Software interface: Command-line user interface
  • Language: Python
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: The MIT License
    • Cost: Free
  • Version name: -
    • Maturity: Stable
  • Credit: Sloan Research Fellowship, National Science Foundation (NSF), National Institute of General Medical Sciences
  • Contact: Jacob Pritt jacobpritt _at_ gmail.com | Ben Langmead langmea _at_ cs.jhu.edu
  • Collection: -

Publications

Pritt J, Langmead B "Boiler: lossy compression of RNA-seq alignments using coverage vectors." Nucleic Acids Res. 2016 Sep 19;44(16):e133. Jun 13. https://doi.org/10.1093/nar/gkw540
PMID: 27298258
PMCID: PMC5027496


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