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ECLAIR

ECLAIR

ECLAIR (Ensemble Cell Lineage Analysis with Improved Robustness) is a tool to cluster cell lineages in single-cell RNA-seq (scRNA-seq) data. The ECLAIR algorithm analyses in three steps: 1. ensemble generation, 2. consensus clustering, and 3. tree combination.

Topic

RNA-seq

Details

  • Operation: RNA-Seq analysis; Expression profile clustering
  • Software interface: Command-line user interface
  • Language: Python
  • Operating system: Linux; Mac OS X
  • License: The MIT licence
  • Cost: Free
  • Version name: -
  • Credit: Claudia Barr Award, the National Institutes of Health (NIH).
  • Contact: gcyuan _at_ jimmy.harvard.edu
  • Collection: -

Publications

Giecold G, Marco E, Garcia SP, Trippa L, Yuan GC "Robust Lineage Reconstruction From High-Dimensional Single-Cell Data" Nucleic Acids Res. 2016 Aug 19;44(14):e122. https://doi.org/10.1093/nar/gkw452
PMID: 27207878
PMCID: PMC5001598


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