A pipeline tool to assemble and annotate transcriptomes for RNA-seq data. The FRAMA algorithm uses a reference transcriptome and makes de novo assemblies, assigns gene symbols, detects fusions and constructs scaffolds, and annotates contigs.
RNA-seq; Sequence assembly
Bens M, Sahm A, Groth M, Jahn N, Morhart M, Holtze S, Hildebrandt TB, Platzer M, Szafranski K "FRAMA: from RNA-seq data to annotated mRNA assemblies." BMC Genomics. 2016 Jan 14;17:54. https://doi.org/10.1186/s12864-015-2349-8
PMID: 26763976
PMCID: PMC4712544
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