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OLego

OLego

A tool for mapping of spliced mRNA-seq reads. The OLego algorithm uses the Burrows-Wheeler transform for the mapping of seeds, splice junctions, and detection of exons. The algorithm also allows multiple threads.

Topic

Genomics; RNA-seq

Details

  • Operation: Sequence alignment; Read mapping
  • Software interface: Command-line user interface
  • Language: C++
  • Operating system: Linux; Mac OS X
  • License: GNU General Public License v3
  • Cost: Free
  • Version name: 1.1.5
  • Maturity: Mature
  • Credit: National Institutes of Health (NIH), National Basic Research Program of China
  • Contact: cz2294 _at_ columbia.edu
  • Collection: -

Publications

Wu J, Anczukow O, Krainer AR, Zhang MQ, Zhang C "OLego: fast and sensitive mapping of spliced mRNA-Seq reads using small seeds." Nucleic Acids Res. 2013 May 1;41(10):5149-63. Apr 9. https://doi.org/10.1093/nar/gkt216
PMID: 23571760
PMCID: PMC3664805


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