demuxlet is a tool to multiplex barcoded droplet single-cell RNA-seq (scRNA-seq) data. The demuxlet algorithm uses a natural genetic variation to assign the identity of each droplet with a single cell and droplets containing two cells.
Gene expression; RNA-Seq
Kang HM, Subramaniam M, Targ S, Nguyen M, Maliskova L, McCarthy E, Wan E, Wong S, Byrnes L, Lanata CM, Gate RE, Mostafavi S, Marson A, Zaitlen N, Criswell LA, Ye CJ "Multiplexed Droplet Single-Cell RNA-sequencing Using Natural Genetic Variation" Nat Biotechnol. 2018 Jan;36(1):89-94. https://doi.org/10.1038/nbt.4042
PMID: 29227470
PMCID: PMC5784859
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