scTDA (single-cell topological data analysis) is a Python library for the analysis of single-cell RNA-seq data. The scTDA algorithm uses an unsupervised statistical structure to characterize cellular states. It is non-linear and model-independent.
RNA-seq; Gene expression
Rizvi AH, Camara PG, Kandror EK, Roberts TJ, Schieren I, Maniatis T, Rabadan R "Single-cell topological RNA-seq analysis reveals insights into cellular differentiation and development." Nat Biotechnol. 2017 Jun;35(6):551-560. https://doi.org/10.1038/nbt.3854
PMID: 28459448
PMCID: PMC5569300
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