A pipeline tool for analysis of RNA-seq data comprising sample-specific barcodes and unique molecular identifiers. The zUMIs algorithm can identify cells by a read distribution. Besides, it has a function to downsample varying library sizes.
RNA-seq; Mapping; Sequence analysis
Parekh S, Ziegenhain C, Vieth B, Enard W, Hellmann I "zUMIs - A fast and flexible pipeline to process RNA sequencing data with UMIs." Gigascience. 2018 Jun 1;7(6). pii: 5005022. https://doi.org/10.1093/gigascience/giy059
PMID: 29846586
PMCID: PMC6007394
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