HIFIASM is a genome assembler that takes advantage of the PacBio HiFi reads. It implements an algorithm that preserves the continuity of all haplotypes for the purpose of phasing the genome. It also has the capability like the Canu assembler to use parental short reads input to perform trio-binned genome assembly. This tool claims to have the ability to assemble a human genome in several hours on a single machine.
Cheng H, Concepcion GT, Feng X, Zhang H, Li H "Haplotype-resolved de novo assembly using phased assembly graphs with hifiasm." Nat Methods, 2021 https://doi.org/10.1038/s41592-020-01056-5
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