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MaCH-Admix

MaCH-Admix

MaCH-admix is a tool for genotype imputation, having added features compared to the MaCH 1.0 tool. The MaCH-admix algorithm does piecewise selection of a reference to tailor-make it fit for a target person. Also, the algorithm allows the use of standard reference panels and independent, calibrated parameters by separating imputation itself from parameter estimation.

Topic

Population genetics

Details

  • Operation: Reference identification; Imputation
  • Software interface: Command-line user interface
  • Language: C++
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Other
  • Cost: Free
  • Version name: 2.0.203
  • Maturity: Stable
  • Credit: The National Institutes of Health (NIH)
  • Contact: yunli _at_ med.unc.edu | Eric Yi Liu liuyi _at_ cs.unc.edu
  • Collection: -

Publications

Liu EY, Li M, Wang W, Li Y "MaCH-admix: genotype imputation for admixed populations." Genet Epidemiol. 2013 Jan;37(1):25-37. https://doi.org/10.1002/gepi.21690
PMID: 23074066
PMCID: PMC3524415

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