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Minimac2

Minimac2

Minimac2 is a tool for genotype imputation. The Minimac2 Algorithm is a computationally efficient implementation of MaCH algorithm, works on phased genotypes and can handle large reference panels up to hundreds of thousands of haplotypes. A multiprocessor version, minimac2-omp is available from the download page.

Topic

Population genetics

Details

  • Operation: Imputation
  • Software interface: Command-line user interface
  • Language: C++;C
  • Operating system: Linux
  • License: Other
  • Cost: Free
  • Version name: 2014.9.15
  • Maturity: Stable
  • Credit: National Institutes of Health (NIH)
  • Contact: Goncalo Abecasis goncalo _at_ umich.edu | Christian Fuchsberger cfuchsb _at_ umich.edu
  • Collection: Minimac

Publications

Fuchsberger C, Abecasis GR, Hinds DA "minimac2: faster genotype imputation." Bioinformatics. 2015 Mar 1;31(5):782-4. 2014 Oct 22. https://doi.org/10.1093/bioinformatics/btu704
PMID: 25338720
PMCID: PMC4341061

Das S, Forer L, Schonherr S, Sidore C, Locke AE, Kwong A, Vrieze SI, Chew EY, Levy S, McGue M, Schlessinger D, Stambolian D, Loh PR, Iacono WG, Swaroop A, Scott LJ, Cucca F, Kronenberg F, Boehnke M, Abecasis GR, Fuchsberger C "Next-generation genotype imputation service and methods." Nat Genet. 2016 Oct;48(10):1284-1287. https://doi.org/10.1038/ng.3656
PMID: 27571263
PMCID: PMC5157836

Download and documentation


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