A program to create multiple sequence alignments of a large number of sequences. Prominent features are rapid sequence distance computation using k-mer counting, a profile function computing a log-expectation scores, and tree-dependent partitioning of the sequences.
Genomics; Sequencing; Sequence analysis
Edgar RC "MUSCLE: multiple sequence alignment with high accuracy and high throughput." Nucleic Acids Res. 2004 ;32(5) https://doi.org/10.1093/nar/gkh340
PMID: 15034147
PMCID: PMC390337
Edgar RC "MUSCLE: a multiple sequence alignment method with reduced time and space complexity." BMC Bioinformatics. 2004 Aug 19;5:113. https://doi.org/10.1186/1471-2105-5-113
PMID: 15318951
PMCID: PMC517706
If you find errors, please report here.
SECTIONS
TutorialsFind thousands of Bioinformatics and Life Science software tools and databases in the newly launched
Ads