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cgDNA

cgDNA

cgDNA is a tool to make a DNA molecule in the minimal free energy configuration. The cgDNA algorithm has functions for computing the associated stiffness in the specific energy configuration and comparisons between multiple DNA shapes. The input and output are Curves+ and PDB atom coordinate -formats.

Topic

Nucleic acid structure analysis

Details

  • Operation: Nucleic acid structure prediction
  • Input: Curves+, PDB atomic coordinates
  • Output: -
  • Software interface: Command-line user interface
  • Language: Matlab
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Not stated
  • Cost: Free
  • Version name: 1.0
  • Credit: Swiss National Science Foundation
  • Contact: john.maddocks _at_ epfl.ch
  • Collection: -

Publications

Petkevičiūtė D, Pasi M, Gonzalez O, Maddocks JH "cgDNA: a software package for the prediction of sequence-dependent coarse-grain free energies of B-form DNA." Nucleic Acids Res, 2014 https://doi.org/10.1093/nar/gku825
PMID: 25228467


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