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XTandemPipeline

XTandemPipeline

X!TandemPipeline is a pipeline tool to filter and group proteins and peptides from tandem mass spectra (MS/MS) data. The X!TandemPipeline reads X!Tandem XML, MASCOT, TPP pepXML, PSI mzIdentML results. The X!TandemPipeline algorithm includes several filters based on statistics on protein levels, a filter to groups redundancy, handling of phosphoproteomic datasets, search and sort, XIC browser, comparison of theoretical isotope patterns to measured MS1 XIC area, and can export data to MS Office 2010.

Topic

Proteomics; Proteomics experiment

Details

  • Operation: Blind peptide database search; PTM identification; Peptide identification; Peptide database search; Data handling; Protein identification; Comparison; Filtering; Target-Decoy; Mass spectrum visualisation
  • Software interface: Graphical user interface
  • Language: Java
  • Operating system: Linux; Microsoft Windows
  • License: GNU General Public License v3
  • Cost: Free
  • Version name: 0.4.3
  • Credit: -
  • Contact: langella _at_ moulon.inra.fr | celine.henry _at_ inrae.fr | lydie.oliveira-correia _at_ inrae.fr | | aaron.millan-oropeza _at_ inrae.fr | veronique.monnet _at_ inrae.fr
  • Collection: -

Publications

Muth T, Vaudel M, Barsnes H, Martens L, Sickmann A "XTandem Parser: an open-source library to parse and analyse X!Tandem MS/MS search results." Proteomics. 2010 Apr;10(7):1522-4. https://doi.org/10.1002/pmic.200900759
PMID: 20140905


Langella O, Valot B, Balliau T, Blein-Nicolas M, Bonhomme L, Zivy M "X!TandemPipeline: A Tool to Manage Sequence Redundancy for Protein Inference and Phosphosite Identification." J. Proteome Res. 2017; 16(2):494-503 https://doi.org/10.1021/acs.jproteome.6b00632
PMID: 27990826


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