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MetaProteomeAnalyzer

MetaProteomeAnalyzer

MetaProteomeAnalyzer (MPA) is a tool for the analysis and interpretation of metaproteomics and proteomics data. The MetaProteomeAnalyzer supports X!Tandem, OMSSA, and Mascot.
The MetaProteomeAnalyzer includes functions for project management for MS/MS experiments, shotgun proteomics data analysis, integration of search algorithms of Comet, MS-GF+ and X!Tandem, re-analysis of results in mzIdentML format, analysis of taxa, ontologies, pathways and enzymes, grouping of redundant protein hits, label-free quantification, among others.

Topic

Proteomics; Proteomics experiment

Details

  • Operation: Peptide database search
  • Software interface: Graphical user interface, command-line user interface
  • Language: Java
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Apache License v2
  • Cost: Free
  • Version name: 3.4
  • Credit: Deutsche Forschungsgemeinschaft, NCI-ITCR, German Environmental Foundation(DBU), the Federal Ministry of Food, Agriculture, and Consumer Protection (BMELV), the Agency forRenewable Resources (FNR), Ghent University (Multidisciplinary Research Partnership“Bioinfor-matics: from nucleotides to networks”), the IWT SBO grant “INSPECTOR”, the EU FP7 PRIME-XS project.
  • Contact: rapp _at_ mpi-magdeburg.mpg.de
  • Collection: -

Publications

Winkler R "MASSyPup--an 'out of the box' solution for the analysis of mass spectrometry data." J Mass Spectrom 2014; 49(1):37-42 https://doi.org/10.1002/jms.3314
PMID: 24446261


Muth T, Kohrs F, Heyer R, Benndorf D, Rapp E, Reichl U, Martens L, Renard BY "MPA Portable: A Stand-Alone Software Package for Analyzing Metaproteome Samples on the Go." Anal. Chem. 2018; 90(1):685-689 https://doi.org/10.1021/acs.analchem.7b03544
PMID: 29215871
PMCID: PMC5757220


Muth T, Behne A, Heyer R, Kohrs F, Benndorf D, Hoffmann M, Lehtevä M, Reichl U, Martens L, Rapp E "The MetaProteomeAnalyzer: a powerful open-source software suite for metaproteomics data analysis and interpretation." J. Proteome Res. 2015; 14(3):1557-65 https://doi.org/10.1021/pr501246w
PMID: 25660940


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